S. mutans, Lactobacilli 및 Actinomyces에 대한 수종의 Propolis추출물의 항세균효과
The Antibacterial Effects of Some Propolis Constituents against S mutans, Lactobacilli and Actinomyces
유영관, 김은경, 김주심, 신효근,
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유영관 ( ) - 전북대학교 치과대학 예방치학교실
김은경 ( ) - 전북대학교 치과대학 예방치학교실
김주심 ( ) - 전북대학교 치과대학 예방치학교실
신효근 ( ) - 전북대학교 치과대학 예방치학교실
KMID : 0355419960200010065
Abstract
Propolis, the resinous hive product collected by bees, has antibacterial and anti-inflammatory activities, and anesthetic action. Some compounds detectable in the extract of propolis, such as caffeic acid, cinnamic acid methylester, cinnamic acid ethyiester, chrysin, quercetin, and genistein, show antimicrobial activity. In this study, we examined the inhibitory effects of propolis on bacterial growth of Streptococcus mutans KCTC 3065(serotype c), Lactobacillus acidophilus KCTC 3111, and Actinomyces naeslundii KCTC 9013 by the CFU and growth inhibition zone measurement when these species were cultured at the concentration of 1, 0.1 mg/ml in the propolis. The results, in the S mutans, L. acidophilus, and A. naeslundii the inhibitory effects of cinnamic acid methylester and cinnamic acid ethylester were significantly higher than those of caffeic acid, chrysin, quercetin and genistein at the concentration of lmg/ml(P<0.01). In the S. mutans, the inhibitory effect of caffeic acid of 0.1mg/ml was significantly higher than that of caffeic acid of 1mg/ml(P<0.01). In the L. acidophius and A. naeslundii, the inhibitory effects of caffeic acid, chrysin, quercetin and genistein was significantly higher than that of control at the concentration of 1 mg/ml (P<0.01).
키워드
Mutans streptococci;Lactobacilli;Actinomyces;Propolis;항세균효과
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